Research Studies
We currently have over 30 research studies in set up, recruitment or follow up. Our research portfolio is diverse and ranges from supporting complex single centre studies to national multicentre randomised controlled trials. We receive funding from a variety of NIHR, Research Council and charitable funding streams. In total, our research studies cover over 400 sites and include more than 28,000 research participants.
Although we take on studies in a wide range of therapeutic areas, our main research fields are: cardiovascular, diabetes, dementia, musculoskeletal, psychology, respiratory and stroke. Within these we are investigating medical interventions, screening, rehabilitation, lifestyle modifications and health service delivery.
We have experience in designing and running a wide variety of studies, including trials of complex interventions, clinical investigations of medical devices, CTIMPs, behavioural interventions and trials utilising routine data. We have experience undertaking RCTs in both Primary and Secondary care and within the Care Home sector. We also undertake methodological research.
We are unable to support studies without funding. Funded single centre, and small feasibility trials may be considered for adoption by the CTU if there is a clear strategy of development to deliver a definitive phase III trial.
Please contact us for further information.
Discover more about some of our current research projects below.
Discover our ongoing studies:
Automated insulin Delivery Amongst Pregnant women with Type 1 diabetes
Chief Investigator: Prof Helen Murphy, University of East Anglia
Click here to learn more
A Proof of Concept Study for Vitamin A Nasal Drops in Post-Viral Olfactory Loss
Click here to learn more
At-Risk Registers Integrated into primary care to Stop Asthma crises in the UK
A pragmatic cluster randomised trial with nested economic and process evaluations examining the effects of integrating at-risk asthma registers into primary care with internet-based training and support
Chief Investigator: Prof Andrew Wilson, University of East Anglia
Click here to learn more
The impact of acute systemic inflammation upon cerebrospinal fluid and blood biomarkers of brain inflammation and injury in dementia: A study in acute hip fracture and memory clinic patients
Chief Investigator: Prof Chris Fox, University of East Anglia
A randomised controlled trial of a complex intervention to prevent return to smoking postpartum
Chief Investigator: Prof Caitlin Notley, University of East Anglia
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Adapting and testing an intervention for carers of people with dementia
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Development of a System to Provide an Automatic Diagnosis for Vestibular Conditions
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CompreHensive geriAtRician-led MEdication Review
Chief Investigators: Professor Debi Bhattacharya, University of Leicester and Professor David Wright, University of Leicester
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Cessation of Smoking Trial in the Emergency Department
Chief Investigators: Dr Ian Pope and Prof Caitlin Notley, University of East Anglia
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Cognitive Behavioural Therapy for the treatment of post-traumatic stress disorder (PTSD) in youth exposed to multiple traumatic stressors: a phase II randomised controlled trial.
Chief Investigator: Dr Richard Meiser-Stedman, University of East Anglia
Estimating the effectiveness and cost-effectiveness of a complex intervention to increase care home staff influenza vaccination rates
RCT of group CBT for men with intellectual and/or developmental disabilities and harmful sexual behavior
A feasibility study to assess the design of a multi-centre randomised controlled trial of the clinical and cost-effectiveness of a caregiving intervention for people following hip fracture surgery.
Chief Investigator: Prof Toby Smith, University of East Anglia
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Interpersonal Counselling for Adolescent Depression delivered by Youth Mental Health Workers without Core Professional Training: A Feasibility Randomised Controlled Trial
Development, evaluation and implementation of molecular diagnostics for hospital-acquired and ventilator-associated pneumonia in diverse UK hospital settings
Chief Investigators: Dr Vanya Gant, University College London and Prof David Livermore, University of East Anglia
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A feasibility study to assess the design of a multi-centre randomised controlled trial of the clinical and cost-effectiveness of a caregiving intervention for people with chronic musculoskeletal pain
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Risk Factors for the Development of Bilateral Ménière's Disease and the Establishment of a National Ménière's Disease Registry
Chief Investigator: Dr John Phillips, Norfolk & Norwich University Hospital
Practical management of cognitive and neuropsychiatric symptoms in MND
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A Randomised, Double-Blind, Placebo-Controlled, Crossover Design, Phase Iib Clinical Trial to Evaluate the Efficacy and Safety of Oral Atomoxetine for the Treatment of Cognitive and Behavioural Change in Participants with Progressive Supranuclear Palsy Syndromes.
Chief Investigator: Professor James B. Rowe, University of Cambridge
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Evaluating Palin Stammering Therapy for School Children versus Treatment as Usual: a feasibility trial
Supportive exercise programmes for accelerating recovery after major abdominal cancer surgery
Chief Investigators: Mr James Hernon, Norfolk & Norwich University Hospital and Professor John Saxton, Northumbria University
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The efficacy and mechanisms of action of n-3 poly-unsaturated fatty acid supplementation in people with non-steroidal exacerbated airways disease and uncontrolled asthma
Chief Investigator: Prof Andrew Wilson, University of East Anglia
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Feasibility randomised controlled trial of a smoking cessation smartphone app that delivers ‘context aware’ behavioural support in real time
Chief Investigator: Dr Felix Naughton, University of East Anglia
A Randomised controlled trial of Energetic Activity for Depression in Young people
Chief Investigator: Dr Daksha Trivedi
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Improving the wellbeing of Children in Care through a group intervention for foster carers: a randomised controlled trial
Chief Investigator: Prof Nick Midgley, University College London
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To determine the efficacy and safety of faecal microbiome transplantation for ME/CFS
Lead Investigator: Prof Simon Carding, Quadram Institute
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Research on Efficacy of Teriparatide Use in the Return of recruits
to Normal duty
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Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole
Chief Investigator: Prof Andrew Wilson, University of East Anglia
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Tailoring evidence-based psychological therapY for People with common mental disorder including Psychotic EXperiences
Chief Investigator: Prof Jesus Perez, University of Cambridge
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Read more about some of our previous research projects:
A randomised feasibility study of serial magnetic resonance imaging to reduce treatment times in Charcot neuroarthropathy in people with diabetes
Click here to read the protocol paper
Comparison of the JOURNEY II Bi-Cruciate Stabilised and GENESIS II Total Knee Arthroplasty in Performance and functional Ability
Chief Investigators: Professor Iain McNamara, Norfolk and Norwich University Hospital, and Dr Celia Clarke, University of East Anglia
Click here to read the protocol paper
The Care Homes Independent Prescriber Pharmacist Study
Chief Investigator: Prof David Wright, University of East Anglia
Click here to learn more
The Efficacy and Mechanism Evaluation of Treating Idiopathic Pulmonary fibrosis with the Addition of Co-trimoxazole
Click here to read the results
A multi-centre cluster randomised controlled trial to evaluate the Guide to Action Care Home (GtACH) fall prevention programme in old age UK care homes
Chief Investigator: Prof Pip Logan, University of Nottingham
Click here to learn more
Click here to read the results
Study of Mirtazapine or carBamazepine for Agitation in Dementia
Chief Investigator: Prof Sube Banerjee, Brighton and Sussex Medical School
Click here to read the results